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Identification of the metabolites of polybrominated diphenyl ether 99 and its related cytochrome P450s()
OBJECTIVE: To investigate the metabolites of polybrominated diphenyl ether 99 (BDE-99) and its related cytochrome P450s in an in vitro system. METHODS: Rat primary hepatocytes were isolated and treated with BDE-99 for 24-72 h. Metabolites were then extracted from the hepatocytes and media, and detec...
Autores principales: | Dong, Huibin, Li, Ziyin, Man, Xiaoming, Zhou, Jingping, Lu, Huiyuan, Wang, Shoulin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596558/ https://www.ncbi.nlm.nih.gov/pubmed/23554634 http://dx.doi.org/10.1016/S1674-8301(10)60032-2 |
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