Cargando…

Morphological and molecular basis of ovarian serous carcinoma

Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinom...

Descripción completa

Detalles Bibliográficos
Autores principales: Rosen, Daniel G, Zhang, Zhihong, Shan, Weiwei, Liu, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596590/
https://www.ncbi.nlm.nih.gov/pubmed/23554638
http://dx.doi.org/10.1016/S1674-8301(10)60036-X
_version_ 1782262525237133312
author Rosen, Daniel G
Zhang, Zhihong
Shan, Weiwei
Liu, Jinsong
author_facet Rosen, Daniel G
Zhang, Zhihong
Shan, Weiwei
Liu, Jinsong
author_sort Rosen, Daniel G
collection PubMed
description Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinoma; subsequently, we review the history of the evolvement of different grading systems used in ovarian serous cancer; in the end, we focus on characterizing the genetics that underlie the 2-tiered pathways through which ovarian serous cancers are believed to arise: the low-grade and the high-grade pathways.
format Online
Article
Text
id pubmed-3596590
institution National Center for Biotechnology Information
language English
publishDate 2010
publisher Editorial Department of Journal of Biomedical Research
record_format MEDLINE/PubMed
spelling pubmed-35965902013-04-02 Morphological and molecular basis of ovarian serous carcinoma Rosen, Daniel G Zhang, Zhihong Shan, Weiwei Liu, Jinsong J Biomed Res Review Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinoma; subsequently, we review the history of the evolvement of different grading systems used in ovarian serous cancer; in the end, we focus on characterizing the genetics that underlie the 2-tiered pathways through which ovarian serous cancers are believed to arise: the low-grade and the high-grade pathways. Editorial Department of Journal of Biomedical Research 2010-07 /pmc/articles/PMC3596590/ /pubmed/23554638 http://dx.doi.org/10.1016/S1674-8301(10)60036-X Text en © 2010 by the Journal of Biomedical Research. All rights reserved. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/
spellingShingle Review
Rosen, Daniel G
Zhang, Zhihong
Shan, Weiwei
Liu, Jinsong
Morphological and molecular basis of ovarian serous carcinoma
title Morphological and molecular basis of ovarian serous carcinoma
title_full Morphological and molecular basis of ovarian serous carcinoma
title_fullStr Morphological and molecular basis of ovarian serous carcinoma
title_full_unstemmed Morphological and molecular basis of ovarian serous carcinoma
title_short Morphological and molecular basis of ovarian serous carcinoma
title_sort morphological and molecular basis of ovarian serous carcinoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596590/
https://www.ncbi.nlm.nih.gov/pubmed/23554638
http://dx.doi.org/10.1016/S1674-8301(10)60036-X
work_keys_str_mv AT rosendanielg morphologicalandmolecularbasisofovarianserouscarcinoma
AT zhangzhihong morphologicalandmolecularbasisofovarianserouscarcinoma
AT shanweiwei morphologicalandmolecularbasisofovarianserouscarcinoma
AT liujinsong morphologicalandmolecularbasisofovarianserouscarcinoma