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Morphological and molecular basis of ovarian serous carcinoma
Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinom...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596590/ https://www.ncbi.nlm.nih.gov/pubmed/23554638 http://dx.doi.org/10.1016/S1674-8301(10)60036-X |
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author | Rosen, Daniel G Zhang, Zhihong Shan, Weiwei Liu, Jinsong |
author_facet | Rosen, Daniel G Zhang, Zhihong Shan, Weiwei Liu, Jinsong |
author_sort | Rosen, Daniel G |
collection | PubMed |
description | Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinoma; subsequently, we review the history of the evolvement of different grading systems used in ovarian serous cancer; in the end, we focus on characterizing the genetics that underlie the 2-tiered pathways through which ovarian serous cancers are believed to arise: the low-grade and the high-grade pathways. |
format | Online Article Text |
id | pubmed-3596590 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Editorial Department of Journal of Biomedical Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-35965902013-04-02 Morphological and molecular basis of ovarian serous carcinoma Rosen, Daniel G Zhang, Zhihong Shan, Weiwei Liu, Jinsong J Biomed Res Review Serous carcinoma is the most common type of epithelial ovarian cancer. In this review, we provide a comprehensive picture of ovarian serous cancers from multiple aspects: the first part of this review summarizes the morphological, histological, and immunological signatures of ovarian serous carcinoma; subsequently, we review the history of the evolvement of different grading systems used in ovarian serous cancer; in the end, we focus on characterizing the genetics that underlie the 2-tiered pathways through which ovarian serous cancers are believed to arise: the low-grade and the high-grade pathways. Editorial Department of Journal of Biomedical Research 2010-07 /pmc/articles/PMC3596590/ /pubmed/23554638 http://dx.doi.org/10.1016/S1674-8301(10)60036-X Text en © 2010 by the Journal of Biomedical Research. All rights reserved. This work is licensed under a Creative Commons Attribution 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/ |
spellingShingle | Review Rosen, Daniel G Zhang, Zhihong Shan, Weiwei Liu, Jinsong Morphological and molecular basis of ovarian serous carcinoma |
title | Morphological and molecular basis of ovarian serous carcinoma |
title_full | Morphological and molecular basis of ovarian serous carcinoma |
title_fullStr | Morphological and molecular basis of ovarian serous carcinoma |
title_full_unstemmed | Morphological and molecular basis of ovarian serous carcinoma |
title_short | Morphological and molecular basis of ovarian serous carcinoma |
title_sort | morphological and molecular basis of ovarian serous carcinoma |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596590/ https://www.ncbi.nlm.nih.gov/pubmed/23554638 http://dx.doi.org/10.1016/S1674-8301(10)60036-X |
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