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Inhibition of endothelial cell Ca(2+) entry and transient receptor potential channels by Sigma-1 receptor ligands

BACKGROUND AND PURPOSE: The Sigma-1 receptor (Sig1R) impacts on calcium ion signalling and has a plethora of ligands. This study investigated Sig1R and its ligands in relation to endogenous calcium events of endothelial cells and transient receptor potential (TRP) channels. EXPERIMENTAL APPROACH: In...

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Detalles Bibliográficos
Autores principales:	Amer, Mohamed S, McKeown, Lynn, Tumova, Sarka, Liu, Ruifeng, Seymour, Victoria AL, Wilson, Lesley A, Naylor, Jacqueline, Greenhalgh, Katriona, Hou, Bing, Majeed, Yasser, Turner, Paul, Sedo, Alicia, O'Regan, David J, Li, Jing, Bon, Robin S, Porter, Karen E, Beech, David J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2013
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596649/ https://www.ncbi.nlm.nih.gov/pubmed/23121507 http://dx.doi.org/10.1111/bph.12041

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