Comparative domain modeling of human EGF-like module EMR2 and study of interaction of the fourth domain of EGF with chondroitin 4-sulphate()

EMR2 is an EGF-like module containing mucin-like hormone receptor-2 precursor, a G-protein coupled receptor (G-PCR). Mutation in EMR2 causes complicated disorders like polycystic kidney disease (PKD). The structure of EMR2 shows that the fifth domain is comprised of EGF-TM7 helices. Functional assig...

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Detalles Bibliográficos
Autores principales: Rani, Mukta, Dikhit, Manas R., Sahoo, Ganesh C, Das, Pradeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2011
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596701/
https://www.ncbi.nlm.nih.gov/pubmed/23554678
http://dx.doi.org/10.1016/S1674-8301(11)60013-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596701/
https://www.ncbi.nlm.nih.gov/pubmed/23554678
http://dx.doi.org/10.1016/S1674-8301(11)60013-4

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