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Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma()
Exhaled breath nitric oxide (NO) is an accepted asthma biomarker. Lung concentrations of NO and its amino acid precursor, L-arginine, are regulated by the relative expressions of the NO synthase (NOS) and arginase isoforms. Increased expression of arginase I and NOS2 occurs in murine models of aller...
Autores principales: | Bratt, Jennifer M., Zeki, Amir A., Last, Jerold A., Kenyon, Nicholas J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Editorial Department of Journal of Biomedical Research
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596726/ https://www.ncbi.nlm.nih.gov/pubmed/23554705 http://dx.doi.org/10.1016/S1674-8301(11)60041-9 |
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