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Sodium Pyruvate Reduced Hypoxic-Ischemic Injury to Neonatal Rat Brain
BACKGROUND: Neonatal hypoxia-ischemia (HI) remains a major cause of severe brain damage and is often associated with high mortality and lifelong disability. Immature brains are extremely sensitive to hypoxia-ischemia, shown as prolonged mitochondrial neuronal death. Sodium pyruvate (SP), a substrate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596790/ https://www.ncbi.nlm.nih.gov/pubmed/22885415 http://dx.doi.org/10.1038/pr.2012.107 |