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Sodium Pyruvate Reduced Hypoxic-Ischemic Injury to Neonatal Rat Brain

BACKGROUND: Neonatal hypoxia-ischemia (HI) remains a major cause of severe brain damage and is often associated with high mortality and lifelong disability. Immature brains are extremely sensitive to hypoxia-ischemia, shown as prolonged mitochondrial neuronal death. Sodium pyruvate (SP), a substrate...

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Detalles Bibliográficos
Autores principales: Pan, Rui, Rong, Zhihui, She, Yun, Cao, Yuan, Chang, Li-Wen, Lee, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596790/
https://www.ncbi.nlm.nih.gov/pubmed/22885415
http://dx.doi.org/10.1038/pr.2012.107