A genome-wide association study of early menopause and the combined impact of identified variants

Early menopause (EM) affects up to 10% of the female population, reducing reproductive lifespan considerably. Currently, it constitutes the leading cause of infertility in the western world, affecting mainly those women who postpone their first pregnancy beyond the age of 30 years. The genetic aetio...

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Detalles Bibliográficos
Autores principales: Perry, John R. B., Corre, Tanguy, Esko, Tõnu, Chasman, Daniel I., Fischer, Krista, Franceschini, Nora, He, Chunyan, Kutalik, Zoltan, Mangino, Massimo, Rose, Lynda M., Vernon Smith, Albert, Stolk, Lisette, Sulem, Patrick, Weedon, Michael N., Zhuang, Wei V., Arnold, Alice, Ashworth, Alan, Bergmann, Sven, Buring, Julie E., Burri, Andrea, Chen, Constance, Cornelis, Marilyn C., Couper, David J., Goodarzi, Mark O., Gudnason, Vilmundur, Harris, Tamara, Hofman, Albert, Jones, Michael, Kraft, Peter, Launer, Lenore, Laven, Joop S. E., Li, Guo, McKnight, Barbara, Masciullo, Corrado, Milani, Lili, Orr, Nicholas, Psaty, Bruce M., Ridker, Paul M., Rivadeneira, Fernando, Sala, Cinzia, Salumets, Andres, Schoemaker, Minouk, Traglia, Michela, Waeber, Gérard, Chanock, Stephen J., Demerath, Ellen W., Garcia, Melissa, Hankinson, Susan E., Hu, Frank B., Hunter, David J., Lunetta, Kathryn L., Metspalu, Andres, Montgomery, Grant W., Murabito, Joanne M., Newman, Anne B., Ong, Ken K., Spector, Tim D., Stefansson, Kari, Swerdlow, Anthony J., Thorsteinsdottir, Unnur, Van Dam, Rob M., Uitterlinden, André G., Visser, Jenny A., Vollenweider, Peter, Toniolo, Daniela, Murray, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Association Studies Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596848/
https://www.ncbi.nlm.nih.gov/pubmed/23307926
http://dx.doi.org/10.1093/hmg/dds551

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