Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma

Neuroblastoma is a childhood extracranial solid tumour that is associated with a number of genetic changes. Included in these genetic alterations are mutations in the kinase domain of the anaplastic lymphoma kinase (ALK) receptor tyrosine kinase (RTK), which have been found in both somatic and famil...

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Detalles Bibliográficos
Autores principales: Chand, Damini, Yamazaki, Yasuo, Ruuth, Kristina, Schönherr, Christina, Martinsson, Tommy, Kogner, Per, Attiyeh, Edward F., Maris, John, Morozova, Olena, Marra, Marco A., Ohira, Miki, Nakagawara, Akira, Sandström, Per-Erik, Palmer, Ruth H., Hallberg, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597019/
https://www.ncbi.nlm.nih.gov/pubmed/23104988
http://dx.doi.org/10.1242/dmm.010348

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