TNF receptors regulate vascular homeostasis in zebrafish through a caspase-8, caspase-2 and P53 apoptotic program that bypasses caspase-3

Although it is known that tumor necrosis factor receptor (TNFR) signaling plays a crucial role in vascular integrity and homeostasis, the contribution of each receptor to these processes and the signaling pathway involved are still largely unknown. Here, we show that targeted gene knockdown of TNFRS...

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Detalles Bibliográficos
Autores principales: Espín, Raquel, Roca, Francisco J., Candel, Sergio, Sepulcre, María P., González-Rosa, Juan M., Alcaraz-Pérez, Francisca, Meseguer, José, Cayuela, María L., Mercader, Nadia, Mulero, Victoriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597020/
https://www.ncbi.nlm.nih.gov/pubmed/22956347
http://dx.doi.org/10.1242/dmm.010249

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