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Knockdown of Pnpla6 protein results in motor neuron defects in zebrafish

Mutations in patatin-like phospholipase domain containing 6 (PNPLA6), also known as neuropathy target esterase (NTE) or SPG39, cause hereditary spastic paraplegia (HSP). Although studies on animal models, including mice and Drosophila, have extended our understanding of PNPLA6, its roles in neural d...

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Detalles Bibliográficos
Autores principales: Song, Yang, Wang, Molin, Mao, Fei, Shao, Ming, Zhao, Baochang, Song, Zhen, Shao, Changshun, Gong, Yaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597022/
https://www.ncbi.nlm.nih.gov/pubmed/22996643
http://dx.doi.org/10.1242/dmm.009688