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Development of asthmatic inflammation in mice following early-life exposure to ambient environmental particulates and chronic allergen challenge
Childhood exposure to environmental particulates increases the risk of development of asthma. The underlying mechanisms might include oxidant injury to airway epithelial cells (AEC). We investigated the ability of ambient environmental particulates to contribute to sensitization via the airways, and...
Autores principales: | Herbert, Cristan, Siegle, Jessica S., Shadie, Alexander M., Nikolaysen, Stina, Garthwaite, Linda, Hansbro, Nicole G., Foster, Paul S., Kumar, Rakesh K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597029/ https://www.ncbi.nlm.nih.gov/pubmed/23223614 http://dx.doi.org/10.1242/dmm.010728 |
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