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Development of asthmatic inflammation in mice following early-life exposure to ambient environmental particulates and chronic allergen challenge

Childhood exposure to environmental particulates increases the risk of development of asthma. The underlying mechanisms might include oxidant injury to airway epithelial cells (AEC). We investigated the ability of ambient environmental particulates to contribute to sensitization via the airways, and...

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Detalles Bibliográficos
Autores principales: Herbert, Cristan, Siegle, Jessica S., Shadie, Alexander M., Nikolaysen, Stina, Garthwaite, Linda, Hansbro, Nicole G., Foster, Paul S., Kumar, Rakesh K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597029/
https://www.ncbi.nlm.nih.gov/pubmed/23223614
http://dx.doi.org/10.1242/dmm.010728

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