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Overexpression of angiopoietin-1 reduces doxorubicin-induced apoptosis in cardiomyocytes

Doxorubicin (Dox) is a major anticancer chemotherapeutic agent. However, it causes cardiomyopathy due to the side effect of cardiomyocyte apoptosis. We have previously reported that angiopoietin-1 significantly reduced myocardial infarction after ischemic injury and protected cardiomyocytes from oxi...

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Detalles Bibliográficos
Autores principales: Ren, Danyang, Zhu, Quan, Li, Jiantao, Ha, Tuanzhu, Wang, Xiaohui, Li, Yuehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597044/
https://www.ncbi.nlm.nih.gov/pubmed/23554782
http://dx.doi.org/10.7555/JBR.26.20120006