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Memantine combined with environmental enrichment improves spatial memory and alleviates Alzheimer's disease-like pathology in senescence-accelerated prone-8 (SAMP8) mice

Memantine is a N-methyl-D-aspartate (NMDA) receptor antagonist approved for the treatment of moderate to severe Alzheimer's disease (AD). Environmental enrichment (EE) has shown significant beneficial effects on functional improvement in AD. In this study, we sought to determine whether combini...

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Detalles Bibliográficos
Autores principales:	Dong, Jingde, Zhou, Mi, Wu, Xiaoqiang, Du, Mingyang, Wang, Xiaoshan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597048/ https://www.ncbi.nlm.nih.gov/pubmed/23554783 http://dx.doi.org/10.7555/JBR.26.20120053

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