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Activation of Rac1-PI3K/Akt is required for epidermal growth factor-induced PAK1 activation and cell migration in MDA-MB-231 breast cancer cells()

Epidermal growth factor (EGF) may increase cell motility, an event implicated in cancer cell invasion and metastasis. However, the underlying mechanisms for EGF-induced cell motility remain elusive. In this study, we found that EGF treatment could activate Ras-related C3 botulinum toxin substrate 1...

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Detalles Bibliográficos
Autores principales:	Yang, Yu, Du, Jun, Hu, Zhenzhen, Liu, Jiaojing, Tian, Yinhui, Zhu, Yichao, Wang, Le, Gu, Luo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2011
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597073/ https://www.ncbi.nlm.nih.gov/pubmed/23554696 http://dx.doi.org/10.1016/S1674-8301(11)60032-8

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