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Endothelial NOS (NOS3) impairs myocardial function in developing sepsis
Endothelial nitric oxide synthase (NOS)3-derived nitric oxide (NO) modulates inotropic response and diastolic interval for optimal cardiac performance under non-inflammatory conditions. In sepsis, excessive NO production plays a key role in severe hypotension and myocardial dysfunction. We aimed to...
Autores principales: | van de Sandt, Annette M., Windler, Rainer, Gödecke, Axel, Ohlig, Jan, Zander, Simone, Reinartz, Michael, Graf, Jürgen, van Faassen, Ernst E., Rassaf, Tienush, Schrader, Jürgen, Kelm, Malte, Merx, Marc W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597270/ https://www.ncbi.nlm.nih.gov/pubmed/23397596 http://dx.doi.org/10.1007/s00395-013-0330-8 |
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