Making Ends Meet: Microwave-Accelerated Synthesis of Cyclic and Disulfide Rich Proteins Via In Situ Thioesterification and Native Chemical Ligation

The development of synthetic methodologies for cyclic peptides is driven by the discovery of cyclic peptide drug scaffolds such as the plant-derived cyclotides, sunflower trypsin inhibitor 1 (SFTI-1) and the development of cyclized conotoxins. Currently, the native chemical ligation reaction between...

Descripción completa

Detalles Bibliográficos
Autores principales: Gunasekera, Sunithi, Aboye, Teshome L., Madian, Walid A., El-Seedi, Hesham R., Göransson, Ulf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597280/
https://www.ncbi.nlm.nih.gov/pubmed/23504256
http://dx.doi.org/10.1007/s10989-012-9331-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597280/
https://www.ncbi.nlm.nih.gov/pubmed/23504256
http://dx.doi.org/10.1007/s10989-012-9331-y

Ejemplares similares