Cargando…

Resveratrol inhibits angiotensin II-induced ERK1/2 activation by downregulating quinone reductase 2 in rat vascular smooth muscle cells

Our previous studies showed that resveratrol could inhibit the proliferation of vascular smooth muscle cells (VSMCs) and repress mRNA and protein expression of quinone reductase 2 (NQO2). This study further explored the potential mechanisms whereby resveratrol inhibits the proliferation of rat VSMCs...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Xiwen, Wang, Yao, Yang, Weiwei, Hou, Xiaofeng, Zou, Jiangang, Cao, Kejiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Editorial Department of Journal of Biomedical Research 2012
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597326/ https://www.ncbi.nlm.nih.gov/pubmed/23554738 http://dx.doi.org/10.1016/S1674-8301(12)60019-0

Ejemplares similares

Arrhythmogenic properties of dismantling cadherin-mediated adhesion in murine hearts()
por: Zhu, Hongjun, et al.
Publicado: (2010)

Sustained Downregulation of Vascular Smooth Muscle Acta2 After Transient Angiotensin II Infusion: A New Model of “Vascular Memory”
por: Pothen, Lucie, et al.
Publicado: (2022)

Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives
por: Cassagnes, Laure-Estelle, et al.
Publicado: (2017)

The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2)
por: Winger, Jonathan A, et al.
Publicado: (2009)

Atypical Features of Thermus thermophilus Succinate:Quinone Reductase
por: Kolaj-Robin, Olga, et al.
Publicado: (2013)

Neuroprotective Properties of Quinone Reductase 2 Inhibitor M-11, a 2-Mercaptobenzimidazole Derivative
por: Voronin, Mikhail V., et al.
Publicado: (2021)

Resveratrol blocks Akt activation in angiotensin II- or EGF-stimulated vascular smooth muscle cells in a redox-independent manner
por: Schreiner, Cornelia E., et al.
Publicado: (2011)

Expanding the Physiological Role of Aryl-Alcohol Flavooxidases as Quinone Reductases
por: Ferreira, Patricia, et al.
Publicado: (2023)

Increased Response to β(2)-Adrenoreceptor Stimulation Augments Inhibition of I(Kr) in Heart Failure Ventricular Myocytes
por: Wang, Hegui, et al.
Publicado: (2012)

Exendin-4 Prevents Vascular Smooth Muscle Cell Proliferation and Migration by Angiotensin II via the Inhibition of ERK1/2 and JNK Signaling Pathways
por: Nagayama, Kosuke, et al.
Publicado: (2015)

Angiotensin (1-7) Inhibits Ang II-mediated ERK1/2 Activation by Stimulating MKP-1 Activation in Vascular Smooth Muscle Cells
por: Sousa-Lopes, Alejandra, et al.
Publicado: (2020)

IKKε knockout alleviates angiotensin II-induced apoptosis and excessive autophagy in vascular smooth muscle cells by regulating the ERK1/2 pathway
por: Chen, Ganyi, et al.
Publicado: (2021)

Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer’s disease phenotype in mice
por: Gould, Nathaniel L., et al.
Publicado: (2023)

Modulation of Akt and ERK1/2 Pathways by Resveratrol in Chronic Myelogenous Leukemia (CML) Cells Results in the Downregulation of Hsp70
por: Banerjee Mustafi, Soumyajit, et al.
Publicado: (2010)

Crystal Structure of ChrR—A Quinone Reductase with the Capacity to Reduce Chromate
por: Eswaramoorthy, Subramaniam, et al.
Publicado: (2012)

Angiotensin II Requires Zinc and Downregulation of the Zinc Transporters ZnT3 and ZnT10 to Induce Senescence of Vascular Smooth Muscle Cells
por: Patrushev, Nikolay, et al.
Publicado: (2012)

GPR30 decreases with vascular aging and promotes vascular smooth muscle cells maintaining differentiated phenotype and suppressing migration via activation of ERK1/2
por: Huang, Fang, et al.
Publicado: (2016)

Functional angiotensin II receptors in cultured vascular smooth muscle cells
Publicado: (1982)

Different Effects of Angiotensin II and Angiotensin-(1-7) on Vascular Smooth Muscle Cell Proliferation and Migration
por: Zhang, Feng, et al.
Publicado: (2010)

Ghrelin Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells through the ERK Pathway
por: Liang, Qiu-Hua, et al.
Publicado: (2012)

Resveratrol's Impact on Vascular Smooth Muscle Cells Hyporeactivity: The Role of Rho-Kinase Inhibition
por: Wiciński, Michał, et al.
Publicado: (2020)

Genomic Analyses of the Quinol Oxidases and/or Quinone Reductases Involved in Bacterial Extracellular Electron Transfer
por: Zhong, Yuhong, et al.
Publicado: (2018)

β2 adrenergic receptor activation governs cardiac repolarization and arrhythmogenesis in a guinea pig model of heart failure
por: Wang, Yao, et al.
Publicado: (2015)

Emerging Role of Angiotensin Type 2 Receptor (AT2R)/Akt/NO Pathway in Vascular Smooth Muscle Cell in the Hyperthyroidism
por: Carrillo-Sepúlveda, Maria Alícia, et al.
Publicado: (2013)

Angiotensin II, Hypercholesterolemia, and Vascular Smooth Muscle Cells: A Perfect Trio for Vascular Pathology
por: St. Paul, Amanda, et al.
Publicado: (2020)

Bmal1 downregulation leads to diabetic cardiomyopathy by promoting Bcl2/IP3R-mediated mitochondrial Ca(2+) overload
por: Zhang, Nannan, et al.
Publicado: (2023)

Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy
por: Mondaca-Ruff, David, et al.
Publicado: (2019)

The 3,4-Quinones of Estrone and Estradiol Are the Initiators of Cancer whereas Resveratrol and N-acetylcysteine Are the Preventers
por: Cavalieri, Ercole, et al.
Publicado: (2021)

iPLA(2)β Overexpression in Smooth Muscle Exacerbates Angiotensin II-Induced Hypertension and Vascular Remodeling
por: Calderon, Lindsay E., et al.
Publicado: (2012)

Protein Arginine Methyltransferase 2 Inhibits Angiotensin II-Induced Proliferation and Inflammation in Vascular Smooth Muscle Cells
por: Zeng, Si-yu, et al.
Publicado: (2018)

NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones.
por: Joseph, P., et al.
Publicado: (1998)

Resveratrol Induces Vascular Smooth Muscle Cell Differentiation through Stimulation of SirT1 and AMPK
por: Thompson, Anne Marie, et al.
Publicado: (2014)

Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing
por: Warren, D T, et al.
Publicado: (2015)

In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids
por: Perez, Jose L, et al.
Publicado: (2010)

Nitroreductase Activites in Giardia lamblia: ORF 17150 Encodes a Quinone Reductase with Nitroreductase Activity
por: Müller, Joachim, et al.
Publicado: (2021)

The Analysis of NADPH Quinone Reductase 1 (NQO1) Polymorphism in Polish Patients with Colorectal Cancer
por: Gorący, Jarosław, et al.
Publicado: (2021)

Exploring ND-011992, a quinazoline-type inhibitor targeting quinone reductases and quinol oxidases
por: Kägi, Jan, et al.
Publicado: (2023)

Testosterone downregulates angiotensin II type-2 receptor via androgen receptor-mediated ERK1/2 MAP kinase pathway in rat aorta
por: Mishra, Jay S, et al.
Publicado: (2016)

NOX4 downregulation leads to senescence of human vascular smooth muscle cells
por: Przybylska, Dorota, et al.
Publicado: (2016)

BMP-2 Overexpression Augments Vascular Smooth Muscle Cell Motility by Upregulating Myosin Va via Erk Signaling
por: Zhang, Ming, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_arnc84furmdtmhh61kl5e8hft2