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Feedback-controlled bolus plus infusion (FC-B/I) method for quantitative drug assessment in living brain with PET
We have developed a feedback-controlled bolus plus infusion (FC-B/I) method for monitoring the interaction between positron emission tomography (PET) ligands and their specific target molecules with PET. The usefulness of the FC-B/I method was evaluated by the direct interaction between [(11)C]raclo...
Autores principales: | Ohba, Hiroyuki, Harada, Norihiro, Nishiyama, Shingo, Kakiuchi, Takeharu, Kimura, Yuichi, Tsukada, Hideo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597362/ https://www.ncbi.nlm.nih.gov/pubmed/22968323 http://dx.doi.org/10.1038/jcbfm.2012.134 |
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