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Delta-like 3 is silenced by methylation and induces apoptosis in human hepatocellular carcinoma

The genetic and epigenetic events of hepatocarcinogenesis are relatively poorly understood. By analyzing genes from human hepatocellular carcinoma (HCC) with restriction landmark genomic scanning, several aberrantly methylated genes, including Delta-like 3 (DLL3), have been isolated. In this study,...

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Detalles Bibliográficos
Autores principales: MAEMURA, KENTARO, YOSHIKAWA, HIROHIDE, YOKOYAMA, KAZUTAKE, UENO, TERUO, KUROSE, HITOMI, UCHIYAMA, KAZUHISA, OTSUKI, YOSHINORI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597457/
https://www.ncbi.nlm.nih.gov/pubmed/23337976
http://dx.doi.org/10.3892/ijo.2013.1778