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The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated genes (cas), form the CRISPR–cas adaptive immune system, which can provide resistance to viruses and plasmids in bacteria and archaea. Here, we use mathematical models, population dynamic experiments, and DN...

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Detalles Bibliográficos
Autores principales: Levin, Bruce R., Moineau, Sylvain, Bushman, Mary, Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597502/
https://www.ncbi.nlm.nih.gov/pubmed/23516369
http://dx.doi.org/10.1371/journal.pgen.1003312