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The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated genes (cas), form the CRISPR–cas adaptive immune system, which can provide resistance to viruses and plasmids in bacteria and archaea. Here, we use mathematical models, population dynamic experiments, and DN...
Autores principales: | Levin, Bruce R., Moineau, Sylvain, Bushman, Mary, Barrangou, Rodolphe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597502/ https://www.ncbi.nlm.nih.gov/pubmed/23516369 http://dx.doi.org/10.1371/journal.pgen.1003312 |
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