Functional Genomic Analysis of the let-7 Regulatory Network in Caenorhabditis elegans

The let-7 microRNA (miRNA) regulates cellular differentiation across many animal species. Loss of let-7 activity causes abnormal development in Caenorhabditis elegans and unchecked cellular proliferation in human cells, which contributes to tumorigenesis. These defects are due to improper expression...

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Detalles Bibliográficos
Autores principales: Hunter, Shaun E., Finnegan, Emily F., Zisoulis, Dimitrios G., Lovci, Michael T., Melnik-Martinez, Katya V., Yeo, Gene W., Pasquinelli, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597506/
https://www.ncbi.nlm.nih.gov/pubmed/23516374
http://dx.doi.org/10.1371/journal.pgen.1003353

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