Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity

Seasonal epidemics of influenza virus result in ∼36,000 deaths annually in the United States. Current vaccines against influenza virus elicit an antibody response specific for the envelope glycoproteins. However, high mutation rates result in the emergence of new viral serotypes, which elude neutral...

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Detalles Bibliográficos
Autores principales: Laidlaw, Brian J., Decman, Vilma, Ali, Mohammed-Alkhatim A., Abt, Michael C., Wolf, Amaya I., Monticelli, Laurel A., Mozdzanowska, Krystyna, Angelosanto, Jill M., Artis, David, Erikson, Jan, Wherry, E. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597515/
https://www.ncbi.nlm.nih.gov/pubmed/23516357
http://dx.doi.org/10.1371/journal.ppat.1003207

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