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Th2 Cell-Intrinsic Hypo-Responsiveness Determines Susceptibility to Helminth Infection
The suppression of protective Type 2 immunity is a principal factor driving the chronicity of helminth infections, and has been attributed to a range of Th2 cell-extrinsic immune-regulators. However, the intrinsic fate of parasite-specific Th2 cells within a chronic immune down-regulatory environmen...
Autores principales: | van der Werf, Nienke, Redpath, Stephen A., Azuma, Miyuki, Yagita, Hideo, Taylor, Matthew D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597521/ https://www.ncbi.nlm.nih.gov/pubmed/23516361 http://dx.doi.org/10.1371/journal.ppat.1003215 |
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