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Localized Lipid Packing of Transmembrane Domains Impedes Integrin Clustering

Integrin clustering plays a pivotal role in a host of cell functions. Hetero-dimeric integrin adhesion receptors regulate cell migration, survival, and differentiation by communicating signals bidirectionally across the plasma membrane. Thus far, crystallographic structures of integrin components ar...

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Detalles Bibliográficos
Autores principales: Mehrbod, Mehrdad, Mofrad, Mohammad R. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597534/
https://www.ncbi.nlm.nih.gov/pubmed/23516344
http://dx.doi.org/10.1371/journal.pcbi.1002948