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Localized Lipid Packing of Transmembrane Domains Impedes Integrin Clustering
Integrin clustering plays a pivotal role in a host of cell functions. Hetero-dimeric integrin adhesion receptors regulate cell migration, survival, and differentiation by communicating signals bidirectionally across the plasma membrane. Thus far, crystallographic structures of integrin components ar...
Autores principales: | Mehrbod, Mehrdad, Mofrad, Mohammad R. K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597534/ https://www.ncbi.nlm.nih.gov/pubmed/23516344 http://dx.doi.org/10.1371/journal.pcbi.1002948 |
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