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The combination of an oxygen-dependent degradation domain-regulated adenovirus expressing the chemokine RANTES/CCL5 and NK-92 cells exerts enhanced antitumor activity in hepatocellular carcinoma
Oncolytic adenoviruses are modified based on adenovirus serotype 5 (Ad5), which belongs to subgroup C and depends on Coxsackie-adenovirus receptor (CAR) to recognize target cells. However, expression of CAR is generally low or lost in certain tumors including hepatocellular carcinoma (HCC). By contr...
Autores principales: | LI, JIANG, LIU, HUI, LI, LINFANG, WU, HONGPING, WANG, CHUNHONG, YAN, ZI, WANG, YING, SU, CHANGQING, JIN, HUAJUN, ZHOU, FUPING, WU, MENGCHAO, QIAN, QIJUN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597539/ https://www.ncbi.nlm.nih.gov/pubmed/23292657 http://dx.doi.org/10.3892/or.2012.2217 |
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