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Effect of 2-Hydroxyethyl Methacrylate on Antioxidant Responsive Element-Mediated Transcription: A Possible Indication of Its Cytotoxicity

BACKGROUND: The resin monomer 2-hydroxyethyl methacrylate (HEMA) is known to be more cytotoxic than methyl methacrylate (MMA). Using a luciferase reporter assay system, we previously showed that MMA activates the glutathione S-transferase alpha 1 gene (Gsta1) promoter through the anti-oxidant respon...

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Detalles Bibliográficos
Autores principales:	Orimoto, Ai, Suzuki, Takahiro, Ueno, Atsuko, Kawai, Tatsushi, Nakamura, Hiroshi, Kanamori, Takao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597541/ https://www.ncbi.nlm.nih.gov/pubmed/23516576 http://dx.doi.org/10.1371/journal.pone.0058907

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