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Therapeutic Efficacy of C-Kit-Targeted Radioimmunotherapy Using 90Y-Labeled Anti-C-Kit Antibodies in a Mouse Model of Small Cell Lung Cancer

Small cell lung cancer (SCLC) is an aggressive tumor and prognosis remains poor. Therefore, the development of more effective therapy is needed. We previously reported that high levels of an anti-c-kit antibody (12A8) accumulated in SCLC xenografts. In the present study, we evaluated the efficacy of...

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Detalles Bibliográficos
Autores principales:	Yoshida, Chisato, Tsuji, Atsushi B., Sudo, Hitomi, Sugyo, Aya, Kikuchi, Tatsuya, Koizumi, Mitsuru, Arano, Yasushi, Saga, Tsuneo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597606/ https://www.ncbi.nlm.nih.gov/pubmed/23516616 http://dx.doi.org/10.1371/journal.pone.0059248

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