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Yellow Fluorescent Protein-Based Assay to Measure GABA(A) Channel Activation and Allosteric Modulation in CHO-K1 Cells
The γ-aminobutyric acid A (GABA(A)) ion channels are important drug targets for treatment of neurological and psychiatric disorders. Finding GABA(A) channel subtype selective allosteric modulators could lead to new improved treatments. However, the progress in this area has been obstructed by the ch...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597608/ https://www.ncbi.nlm.nih.gov/pubmed/23516634 http://dx.doi.org/10.1371/journal.pone.0059429 |