Cargando…

Expanded target and cofactor repertoire for the transcriptional activator LysM from Sulfolobus

Previously, Lrp-like transcriptional regulator LysM from the hyperthermoacidophilic crenarchaeon Sulfolobus solfataricus was proposed to have a single target, the lysWXJK operon of lysine biosynthesis, and a single effector molecule, l-lysine. Here we identify ∼70 novel binding sites for LysM in the...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Ningning, Nguyen Duc, Trong, van Oeffelen, Liesbeth, Muyldermans, Serge, Peeters, Eveline, Charlier, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597687/
https://www.ncbi.nlm.nih.gov/pubmed/23355617
http://dx.doi.org/10.1093/nar/gkt021