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Expanded target and cofactor repertoire for the transcriptional activator LysM from Sulfolobus

Previously, Lrp-like transcriptional regulator LysM from the hyperthermoacidophilic crenarchaeon Sulfolobus solfataricus was proposed to have a single target, the lysWXJK operon of lysine biosynthesis, and a single effector molecule, l-lysine. Here we identify ∼70 novel binding sites for LysM in the...

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Detalles Bibliográficos
Autores principales:	Song, Ningning, Nguyen Duc, Trong, van Oeffelen, Liesbeth, Muyldermans, Serge, Peeters, Eveline, Charlier, Daniel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2013
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597687/ https://www.ncbi.nlm.nih.gov/pubmed/23355617 http://dx.doi.org/10.1093/nar/gkt021

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