Molecular paleontology: a biochemical model of the ancestral ribosome

Ancient components of the ribosome, inferred from a consensus of previous work, were constructed in silico, in vitro and in vivo. The resulting model of the ancestral ribosome presented here incorporates ∼20% of the extant 23S rRNA and fragments of five ribosomal proteins. We test hypotheses that an...

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Detalles Bibliográficos
Autores principales: Hsiao, Chiaolong, Lenz, Timothy K., Peters, Jessica K., Fang, Po-Yu, Schneider, Dana M., Anderson, Eric J., Preeprem, Thanawadee, Bowman, Jessica C., O'Neill, Eric B., Lie, Lively, Athavale, Shreyas S., Gossett, J. Jared, Trippe, Catherine, Murray, Jason, Petrov, Anton S., Wartell, Roger M., Harvey, Stephen C., Hud, Nicholas V., Dean Williams, Loren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597689/
https://www.ncbi.nlm.nih.gov/pubmed/23355613
http://dx.doi.org/10.1093/nar/gkt023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597689/
https://www.ncbi.nlm.nih.gov/pubmed/23355613
http://dx.doi.org/10.1093/nar/gkt023

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