Distinct spatiotemporal patterns and PARP dependence of XRCC1 recruitment to single-strand break and base excision repair

Single-strand break repair (SSBR) and base excision repair (BER) of modified bases and abasic sites share several players. Among them is XRCC1, an essential scaffold protein with no enzymatic activity, required for the coordination of both pathways. XRCC1 is recruited to SSBR by PARP-1, responsible...

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Detalles Bibliográficos
Autores principales: Campalans, Anna, Kortulewski, Thierry, Amouroux, Rachel, Menoni, Hervé, Vermeulen, Wim, Radicella, J. Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597691/
https://www.ncbi.nlm.nih.gov/pubmed/23355608
http://dx.doi.org/10.1093/nar/gkt025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597691/
https://www.ncbi.nlm.nih.gov/pubmed/23355608
http://dx.doi.org/10.1093/nar/gkt025

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