Cargando…

Hyperpolarization-Activated Current (I(h)) Is Reduced in Hippocampal Neurons from Gabra5−/− Mice

Changes in the expression of γ-aminobutyric acid type A (GABA(A)) receptors can either drive or mediate homeostatic alterations in neuronal excitability. A homeostatic relationship between α5 subunit-containing GABA(A) (α5GABA(A)) receptors that generate a tonic inhibitory conductance, and HCN chann...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bonin, Robert P., Zurek, Agnieszka A., Yu, Jieying, Bayliss, Douglas A., Orser, Beverley A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597723/ https://www.ncbi.nlm.nih.gov/pubmed/23516534 http://dx.doi.org/10.1371/journal.pone.0058679

Ejemplares similares

Gabapentin increases expression of δ subunit-containing GABA(A) receptors
por: Yu, Jieying, et al.
Publicado: (2019)

Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(−/−) Mice
por: Fan, Jing, et al.
Publicado: (2016)

A standardized polyherbal preparation POL-6 diminishes alcohol withdrawal anxiety by regulating Gabra1, Gabra2, Gabra3, Gabra4, Gabra5 gene expression of GABA(A) receptor signaling pathway in rats
por: Sharma, Lalit, et al.
Publicado: (2021)

Hyperpolarization-Activated Current (I (h)) in Ganglion-Cell Photoreceptors
por: Van Hook, Matthew J., et al.
Publicado: (2010)

Remodeling of Hyperpolarization-Activated Current, I(h), in Ah-Type Visceral Ganglion Neurons Following Ovariectomy in Adult Rats
por: Qiao, Guo-Fen, et al.
Publicado: (2013)

The mRNA-edited form of GABRA3 suppresses GABRA3-mediated Akt activation and breast cancer metastasis
por: Gumireddy, Kiranmai, et al.
Publicado: (2016)

Tonotopic organization of the hyperpolarization-activated current (I(h)) in the mammalian medial superior olive
por: Baumann, Veronika J., et al.
Publicado: (2013)

Antidepressant Effects of (S)-Ketamine through a Reduction of Hyperpolarization-Activated Current I(h)
por: Kim, Chung Sub, et al.
Publicado: (2020)

Memory Deficits Induced by Inflammation Are Regulated by α5-Subunit-Containing GABA(A) Receptors
por: Wang, Dian-Shi, et al.
Publicado: (2012)

Gabra5 plays a sexually dimorphic role in POMC neuron activity and glucose balance
por: Pei, Zhou, et al.
Publicado: (2022)

Hydroxychloroquine reduces heart rate by modulating the hyperpolarization-activated current I(f): Novel electrophysiological insights and therapeutic potential
por: Capel, Rebecca A., et al.
Publicado: (2015)

Gabra2 is a genetic modifier of Dravet syndrome in mice
por: Hawkins, Nicole A., et al.
Publicado: (2021)

Delayed Effects of Corticosterone on Slow After-Hyperpolarization Potentials in Mouse Hippocampal versus Prefrontal Cortical Pyramidal Neurons
por: Pillai, Anup G., et al.
Publicado: (2014)

Chronic cervical radiculopathic pain is associated with increased excitability and hyperpolarization-activated current (I(h)) in large-diameter dorsal root ganglion neurons
por: Liu, Da-Lu, et al.
Publicado: (2017)

Exercise Reduces H3K9me3 and Regulates Brain Derived Neurotrophic Factor and GABRA2 in an Age Dependent Manner
por: Ionescu-Tucker, Andra, et al.
Publicado: (2021)

Downregulation of Gabra4 expression during alcohol withdrawal is mediated by specific microRNAs in cultured mouse cortical neurons
por: Bekdash, Rola A, et al.
Publicado: (2015)

Cell-Type Specific Development of the Hyperpolarization-Activated Current, Ih, in Prefrontal Cortical Neurons
por: Yang, Sha-Sha, et al.
Publicado: (2018)

Ablation of Gabra5 Influences Corticosterone Levels and Anxiety-like Behavior in Mice
por: Syding, Linn Amanda, et al.
Publicado: (2023)

Reduced excitatory neurotransmission in the hippocampus after inflammation and sevoflurane anaesthesia
por: Khodaei, Shahin, et al.
Publicado: (2023)

Phenotypic variability of GABRA1‐related epilepsy in monozygotic twins
por: Krenn, Martin, et al.
Publicado: (2019)

GABRA1 and GABRB2 Polymorphisms are Associated with Propofol Susceptibility
por: Zeng, Youjie, et al.
Publicado: (2022)

Rapid recovery from K current inactivation on membrane hyperpolarization in molluscan neurons
Publicado: (1984)

Distinct perinatal features of the hyperpolarization-activated non-selective cation current I(h) in the rat cortical plate
por: Battefeld, Arne, et al.
Publicado: (2012)

High and low expression of the hyperpolarization activated current (I (h)) in mouse CA1 stratum oriens interneurons
por: Hewitt, Lauren T., et al.
Publicado: (2021)

Genetic variation in GABRA2 moderates peer influence on externalizing behavior in adolescents
por: Villafuerte, Sandra, et al.
Publicado: (2014)

Characterization of the zebrafish gabra1(sa43718/sa43718) germline loss of function allele confirms a function for Gabra1 in motility and nervous system development
por: Paz, David, et al.
Publicado: (2023)

α5 Subunit-containing GABA(A) receptors mediate a slowly decaying inhibitory synaptic current in CA1 pyramidal neurons following Schaffer collateral activation
por: Vargas-Caballero, Mariana, et al.
Publicado: (2010)

Successful use of perampanel in GABRA1-related myoclonic epilepsy with photosensitivity
por: Olivotto, Sara, et al.
Publicado: (2022)

Expression and properties of hyperpolarization-activated current in rat dorsal root ganglion neurons with known sensory function
por: Gao, L L, et al.
Publicado: (2012)

Mechanotransduction and hyperpolarization-activated currents contribute to spontaneous activity in mouse vestibular ganglion neurons
por: Horwitz, Geoffrey C., et al.
Publicado: (2014)

Cell-surface biotinylation of GABA(A) receptors in mouse hippocampal slices after sevoflurane anesthesia
por: Ariza, Anthony, et al.
Publicado: (2023)

Motivational Effects of Methylphenidate are Associated with GABRA2 Variants Conferring Addiction Risk
por: Duka, Theodora, et al.
Publicado: (2015)

Pathophysiology of and therapeutic options for a GABRA1 variant linked to epileptic encephalopathy
por: Bai, Yun-Fei, et al.
Publicado: (2019)

Gabra2 is a genetic modifier of Scn8a encephalopathy in the mouse*
por: Yu, Wenxi, et al.
Publicado: (2020)

A quantitative trait variant in Gabra2 underlies increased methamphetamine stimulant sensitivity
por: Goldberg, Lisa R., et al.
Publicado: (2021)

Anti-AMPA Receptor Autoantibodies Reduce Excitatory Currents in Rat Hippocampal Neurons
por: Day, Charlotte, et al.
Publicado: (2023)

SUMOylation of the Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 2 Increases Surface Expression and the Maximal Conductance of the Hyperpolarization-Activated Current
por: Parker, Anna R., et al.
Publicado: (2017)

Muscle Contraction during Hyperpolarizing Currents in the Crab
por: Uchitel, O. D., et al.
Publicado: (1974)

Hyperpolarization-activated chloride currents in Xenopus oocytes
Publicado: (1994)

α5GABA(A) receptor deficiency causes autism‐like behaviors
por: Zurek, Agnieszka A., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dff5ooga41r1epai3kol2oslhf