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Current status of drug screening and disease modelling in human pluripotent stem cells

The emphasis in human pluripotent stem cell (hPSC) technologies has shifted from cell therapy to in vitro disease modelling and drug screening. This review examines why this shift has occurred, and how current technological limitations might be overcome to fully realise the potential of hPSCs. Detai...

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Detalles Bibliográficos
Autores principales: Rajamohan, Divya, Matsa, Elena, Kalra, Spandan, Crutchley, James, Patel, Asha, George, Vinoj, Denning, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3597971/
https://www.ncbi.nlm.nih.gov/pubmed/22886688
http://dx.doi.org/10.1002/bies.201200053