High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring

Maternal folic acid supplementation is essential to reduce the risk of neural tube defects. We hypothesize that high levels of folic acid throughout gestation may produce neural networks more susceptible to seizure in offspring. We hence administered large doses of folic acid to rats before and duri...

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Detalles Bibliográficos
Autores principales: Girotto, Fernando, Scott, Lucas, Avchalumov, Yosef, Harris, Jacqueline, Iannattone, Stephanie, Drummond-Main, Chris, Tobias, Rose, Bello-Espinosa, Luis, Rho, Jong M., Davidsen, Jörn, Teskey, G. Campbell, Colicos, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598003/
https://www.ncbi.nlm.nih.gov/pubmed/23492951
http://dx.doi.org/10.1038/srep01465

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598003/
https://www.ncbi.nlm.nih.gov/pubmed/23492951
http://dx.doi.org/10.1038/srep01465

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