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High dose folic acid supplementation of rats alters synaptic transmission and seizure susceptibility in offspring
Maternal folic acid supplementation is essential to reduce the risk of neural tube defects. We hypothesize that high levels of folic acid throughout gestation may produce neural networks more susceptible to seizure in offspring. We hence administered large doses of folic acid to rats before and duri...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598003/ https://www.ncbi.nlm.nih.gov/pubmed/23492951 http://dx.doi.org/10.1038/srep01465 |