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A human tRNA methyltransferase 9-like protein prevents tumour growth by regulating LIN9 and HIF1-α

Emerging evidence points to aberrant regulation of translation as a driver of cell transformation in cancer. Given the direct control of translation by tRNA modifications, tRNA modifying enzymes may function as regulators of cancer progression. Here, we show that a tRNA methyltransferase 9-like (hTR...

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Detalles Bibliográficos
Autores principales:	Begley, Ulrike, Sosa, Maria Soledad, Avivar-Valderas, Alvaro, Patil, Ashish, Endres, Lauren, Estrada, Yeriel, Chan, Clement TY, Su, Dan, Dedon, Peter C, Aguirre-Ghiso, Julio A, Begley, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2013
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598078/ https://www.ncbi.nlm.nih.gov/pubmed/23381944 http://dx.doi.org/10.1002/emmm.201201161

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