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Apoptosis rate and transcriptional response of pancreatic islets exposed to the PPAR gamma agonist Pioglitazone

To explore the molecular pathways underlying thiazolidinediones effects on pancreatic islets in conditions mimicking normo- and hyperglycemia, apoptosis rate and transcriptional response to Pioglitazone at both physiological and supraphysiological glucose concentrations were evaluated. Adult rat isl...

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Detalles Bibliográficos
Autores principales:	Lamounier, Rodrigo N, Coimbra, Cassio N, White, Peter, Costal, Flavia L, Oliveira, Leonardo S, Giannella-Neto, Daniel, Kaestner, Klaus H, Corrêa-Giannella, Maria Lúcia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598339/ https://www.ncbi.nlm.nih.gov/pubmed/23298687 http://dx.doi.org/10.1186/1758-5996-5-1

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