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Attenuated antigen-specific T cell responses in cirrhosis are accompanied by elevated serum interleukin-10 levels and down-regulation of HLA-DR on monocytes
BACKGROUND: Advanced liver disease predisposes to bacterial translocation and endotoxaemia which can contribute to elevated circulating levels of IL-10 and down-regulation of MHC class II on antigen-presenting cells. We sought to evaluate antigen-specific T-cell responses toward common viral antigen...
Autores principales: | Peter, Jack, Frey, Oliver, Stallmach, Andreas, Bruns, Tony |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598528/ https://www.ncbi.nlm.nih.gov/pubmed/23446058 http://dx.doi.org/10.1186/1471-230X-13-37 |
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