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Role of the ABCG8 19H risk allele in cholesterol absorption and gallstone disease
BACKGROUND: Gallstone disease is associated with p.D19H of ABCG8 as well as alterations of cholesterol and bile acid metabolism. However, molecular mechanisms have not been fully elucidated. It is important to understand the link between the sterol transporters ABCG5/8 and NPC1L1 and intestinal chol...
Autores principales: | Renner, Olga, Lütjohann, Dieter, Richter, Dominique, Strohmeyer, André, Schimmel, Silke, Müller, Oliver, Stange, Eduard F, Harsch, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598676/ https://www.ncbi.nlm.nih.gov/pubmed/23406058 http://dx.doi.org/10.1186/1471-230X-13-30 |
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