Cargando…

Alteration of the Thymic T Cell Repertoire by Rotavirus Infection Is Associated with Delayed Type 1 Diabetes Development in Non-Obese Diabetic Mice

Rotaviruses are implicated as a viral trigger for the acceleration of type 1 diabetes in children. Infection of adult non-obese diabetic (NOD) mice with rotavirus strain RRV accelerates diabetes development, whereas RRV infection in infant NOD mice delays diabetes onset. In this study of infant mice...

Descripción completa

Detalles Bibliográficos
Autores principales:	Webster, Nicole L., Zufferey, Christel, Pane, Jessica A., Coulson, Barbara S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598695/ https://www.ncbi.nlm.nih.gov/pubmed/23554993 http://dx.doi.org/10.1371/journal.pone.0059182

Ejemplares similares

Rotavirus Activates Lymphocytes from Non-Obese Diabetic Mice by Triggering Toll-Like Receptor 7 Signaling and Interferon Production in Plasmacytoid Dendritic Cells
por: Pane, Jessica A., et al.
Publicado: (2014)

Rotavirus acceleration of type 1 diabetes in non-obese diabetic mice depends on type I interferon signalling
por: Pane, Jessica A., et al.
Publicado: (2016)

Editing T cell repertoire by thymic epithelial cell-directed gene transfer abrogates risk of type 1 diabetes development
por: Russo, Fabio, et al.
Publicado: (2022)

Thymic selection of the human T cell receptor V beta repertoire in SCID- hu mice
Publicado: (1992)

Quantitative Impact of Thymic Clonal Deletion on the T Cell Repertoire
por: van Meerwijk, Joost P.M., et al.
Publicado: (1997)

Oral Supplementation with Benzylamine Delays the Onset of Diabetes in Obese and Diabetic db-/- Mice
por: Iffiú-Soltesz, Zsuzsa, et al.
Publicado: (2021)

MHC class I expression in intestinal cells is reduced by rotavirus infection and increased in bystander cells lacking rotavirus antigen
por: Holloway, Gavan, et al.
Publicado: (2018)

Quantifying changes in the T cell receptor repertoire during thymic development
por: Camaglia, Francesco, et al.
Publicado: (2023)

Does rotavirus turn on type 1 diabetes?
por: Harrison, Leonard C., et al.
Publicado: (2019)

Antibodies to Human Thymic Epithelium Form Part of the Murine Autoreactive Repertoire
por: Freysdottir, Jona, et al.
Publicado: (2001)

Thymic Alterations in GM2 Gangliosidoses Model Mice
por: Kanzaki, Seiichi, et al.
Publicado: (2010)

Thymically-derived Foxp3(+) regulatory T cells are the primary regulators of type 1 diabetes in the non-obese diabetic mouse model
por: Holohan, Daniel R., et al.
Publicado: (2019)

Thymic B Cell-Mediated Attack of Thymic Stroma Precedes Type 1 Diabetes Development
por: Pinto, Ana Isabel, et al.
Publicado: (2018)

Loss of Pten Disrupts the Thymic Epithelium and Alters Thymic Function
por: Garfin, Phillip M., et al.
Publicado: (2016)

Aging augments obesity-induced thymic involution and peripheral T cell exhaustion altering the “obesity paradox”
por: Vick, Logan V., et al.
Publicado: (2023)

Obesity is associated with an altered baseline and post-vaccination influenza antibody repertoire
por: Abd Alhadi, Marwa, et al.
Publicado: (2021)

Mechanisms shaping the naïve T cell repertoire in the elderly — Thymic involution or peripheral homeostatic proliferation?
por: Qi, Qian, et al.
Publicado: (2014)

High-throughput analysis of the human thymic Vδ1(+) T cell receptor repertoire
por: Di Lorenzo, Biagio, et al.
Publicado: (2019)

Complete Diabetes Protection Despite Delayed Thymic Tolerance in NOD8.3 TCR Transgenic Mice Due to Antigen-Induced Extrathymic Deletion of T Cells
por: Krishnamurthy, Balasubramanian, et al.
Publicado: (2012)

Thymic alterations in mice deficient for the SNARE protein VAMP8/endobrevin
por: Kanwar, Namita, et al.
Publicado: (2008)

Single-Cell Analysis Identifies Thymic Maturation Delay in Growth-Restricted Neonatal Mice
por: Bacon, Wendi A., et al.
Publicado: (2018)

Thymic Stromal Lymphopoietin and Thymic Stromal Lymphopoietin–Conditioned Dendritic Cells Induce Regulatory T-Cell Differentiation and Protection of NOD Mice Against Diabetes
por: Besin, Gilles, et al.
Publicado: (2008)

Pioglitazone alters monocyte populations and stimulates recent thymic emigrants in the BBDZR/Wor type 2 diabetes rat model
por: Gao, Bradley T., et al.
Publicado: (2015)

T Cell Repertoire Diversity Is Decreased in Type 1 Diabetes Patients
por: Tong, Yin, et al.
Publicado: (2016)

Comparative analysis of the repertoire of insulin-reactive B cells in type 1 diabetes-prone and resistant mice
por: Banach, Maureen, et al.
Publicado: (2022)

Genetic Modifiers of Thymic Selection and Central Tolerance in Type 1 Diabetes
por: Kissler, Stephan
Publicado: (2022)

Possible association of rotavirus IgG with cytokine expression levels and dyslipidemia in rotavirus-infected type 1 diabetic children
por: Khalil, Rehab G., et al.
Publicado: (2022)

New approaches to eliciting protective immunity through T cell repertoire manipulation: the concept of thymic vaccination
por: Fridkis-Hareli, Masha, et al.
Publicado: (2004)

Effects of thymic selection of the T cell repertoire on HLA-class I associated control of HIV infection
por: Košmrlj, Andrej, et al.
Publicado: (2010)

Thymic Function and T-Cell Receptor Repertoire Diversity: Implications for Patient Response to Checkpoint Blockade Immunotherapy
por: Cardinale, Antonella, et al.
Publicado: (2021)

Analysis of the intestinal microbial community altered during rotavirus infection in suckling mice
por: Zhao, Wei, et al.
Publicado: (2021)

A maple syrup extract alters lipid metabolism in obese type 2 diabetic model mice
por: Toyoda, Tsudoi, et al.
Publicado: (2019)

Oral Fc-Coupled Preproinsulin Achieves Systemic and Thymic Delivery Through the Neonatal Fc Receptor and Partially Delays Autoimmune Diabetes
por: Corcos, Noémie, et al.
Publicado: (2021)

Mitochondrial alteration in type 2 diabetes and obesity: An epigenetic link
por: Cheng, Zhiyong, et al.
Publicado: (2014)

High-Density Lipoprotein Alterations in Type 2 Diabetes and Obesity
por: Denimal, Damien, et al.
Publicado: (2023)

Thymic B Cells as a New Player in the Type 1 Diabetes Response
por: Greaves, Richard B., et al.
Publicado: (2021)

No association between incidence of type 1 diabetes and rotavirus vaccination in Swedish children
por: Rangert, Amanda, et al.
Publicado: (2023)

Maternal obesity and diabetes may cause DNA methylation alteration in the spermatozoa of offspring in mice
por: Ge, Zhao-Jia, et al.
Publicado: (2014)

Exposure to persistent organic pollutants alters the serum metabolome in non-obese diabetic mice
por: Sinioja, Tim, et al.
Publicado: (2022)

Age-Related Immune Profile of the T Cell Receptor Repertoire, Thymic Recent Output Function, and miRNAs
por: Xu, Yan, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_2dk569tvsrdc6vkfjealdkvida