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Rab GTPases Regulate Endothelial Cell Protein C Receptor-Mediated Endocytosis and Trafficking of Factor VIIa

Recent studies have established that factor VIIa (FVIIa) binds to the endothelial cell protein C receptor (EPCR). FVIIa binding to EPCR may promote the endocytosis of this receptor/ligand complex. Rab GTPases are known to play a crucial role in the endocytic and exocytic pathways of receptors or rec...

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Detalles Bibliográficos
Autores principales:	Nayak, Ramesh C., Keshava, Shiva, Esmon, Charles T., Pendurthi, Usha R., Rao, L. Vijaya Mohan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598704/ https://www.ncbi.nlm.nih.gov/pubmed/23555015 http://dx.doi.org/10.1371/journal.pone.0059304

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