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Advances in the Pathogenesis of Alzheimer’s Disease: Focusing on Tau-Mediated Neurodegeneration

In addition to senile plaques and cerebral amyloid angiopathy, the hyperphosphorylation of tau protein and formation of intraneuronal neurofibrillary tangles (NFTs) represents another neuropathological hallmark in AD brain. Tau is a microtubule-associated protein and localizes predominantly in the a...

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Detalles Bibliográficos
Autores principales:	Duan, Yale, Dong, Suzhen, Gu, Feng, Hu, Yinghe, Zhao, Zheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598890/ https://www.ncbi.nlm.nih.gov/pubmed/23241453 http://dx.doi.org/10.1186/2047-9158-1-24

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