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In Vivo Detection of Human TRPV6-Rich Tumors with Anti-Cancer Peptides Derived from Soricidin

Soricidin is a 54-amino acid peptide found in the paralytic venom of the northern short-tailed shrew (Blarina brevicauda) and has been found to inhibit the transient receptor potential of vallinoid type 6 (TRPV6) calcium channels. We report that two shorter peptides, SOR-C13 and SOR-C27, derived fro...

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Detalles Bibliográficos
Autores principales: Bowen, Chris V., DeBay, Drew, Ewart, H. Stephen, Gallant, Pamela, Gormley, Sean, Ilenchuk, T. Toney, Iqbal, Umar, Lutes, Tyler, Martina, Marzia, Mealing, Geoffrey, Merkley, Nadine, Sperker, Sandra, Moreno, Maria J., Rice, Christopher, Syvitski, Raymond T., Stewart, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598914/
https://www.ncbi.nlm.nih.gov/pubmed/23554944
http://dx.doi.org/10.1371/journal.pone.0058866