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The 1,4-benzodiazepine Ro5-4864 (4-chlorodiazepam) suppresses multiple pro-inflammatory mast cell effector functions

Activation of mast cells (MCs) can be achieved by the high-affinity receptor for IgE (FcεRI) as well as by additional receptors such as the lipopolysaccharide (LPS) receptor and the receptor tyrosine kinase Kit (stem cell factor [SCF] receptor). Thus, pharmacological interventions which stabilize MC...

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Detalles Bibliográficos
Autores principales:	Yousefi, Omid Sascha, Wilhelm, Thomas, Maschke-Neuß, Karin, Kuhny, Marcel, Martin, Christian, Molderings, Gerhard J, Kratz, Felix, Hildenbrand, Bernd, Huber, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598916/ https://www.ncbi.nlm.nih.gov/pubmed/23425659 http://dx.doi.org/10.1186/1478-811X-11-13

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