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The Interplay between Chondrocyte Redifferentiation Pellet Size and Oxygen Concentration
Chondrocytes dedifferentiate during ex vivo expansion on 2-dimensional surfaces. Aggregation of the expanded cells into 3-dimensional pellets, in the presence of induction factors, facilitates their redifferentiation and restoration of the chondrogenic phenotype. Typically 1×10(5)–5×10(5) chondrocyt...
Autores principales: | Babur, Betul Kul, Ghanavi, Parisa, Levett, Peter, Lott, William B., Klein, Travis, Cooper-White, Justin J., Crawford, Ross, Doran, Michael R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598946/ https://www.ncbi.nlm.nih.gov/pubmed/23554943 http://dx.doi.org/10.1371/journal.pone.0058865 |
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