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Visceral Endoderm Expression of Yin-Yang1 (YY1) Is Required for VEGFA Maintenance and Yolk Sac Development
Mouse embryos lacking the polycomb group gene member Yin-Yang1 (YY1) die during the peri-implantation stage. To assess the post-gastrulation role of YY1, a conditional knock-out (cKO) strategy was used to delete YY1 from the visceral endoderm of the yolk sac and the definitive endoderm of the embryo...
Autores principales: | Rhee, Siyeon, Guerrero-Zayas, Mara-Isel, Wallingford, Mary C., Ortiz-Pineda, Pablo, Mager, Jesse, Tremblay, Kimberly D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3598950/ https://www.ncbi.nlm.nih.gov/pubmed/23554936 http://dx.doi.org/10.1371/journal.pone.0058828 |
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