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Induction of human fetal hemoglobin expression by adenosine-2’,3’-dialdehyde
BACKGROUND: Pharmacologic reactivation of fetal hemoglobin expression is a promising strategy for treatment of sickle cell disease and β-thalassemia. The objective of this study was to investigate the effect of the methyl transferase inhibitor adenosine-2’,3’-dialdehyde (Adox) on induction of human...
Autores principales: | He, Yinghong, Rank, Gerhard, Zhang, Miaomiao, Ju, Junyi, Liu, Ronghua, Xu, Zhen, Brown, Fiona, Cerruti, Loretta, Ma, Chi, Tan, Renxiang, Jane, Stephen M, Zhao, Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599103/ https://www.ncbi.nlm.nih.gov/pubmed/23316703 http://dx.doi.org/10.1186/1479-5876-11-14 |
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